Distribution: This syndrome affects men and women equally and occurs in among all races and ethnic groups. Many people with this syndrome get Marfan from their parents due to the fact that this syndrome is a genetic condition. Marfan is a very common disorder and affected about 1 in 5,000 people.
Managementandtreatment: These treatments depend of severity of the condition, this includes a back brace, contact lenses, and glasses. Some surgical procedures include a vitrectomy, endovascualr aneurysm repair, vascular graphing, and heart valve repair. Medications include a beta-blocker and anti hypertensive drugs.
Society and Culture: The severity of the disease depends on the quality of life. Many cases of Marfan does result in a very normal life with some complications and a shortened life expectancy. However, the heart complications, particularly aortic dilation, dissection, rupture, and involvement of the aortic mitral valves, may cause a short life.
Signs of symptoms: Usual features of people with Marfan Syndrome are slightly different for everyone, and they may not all have or experience these symptoms. People affected by Marfan Syndrome are very tall with long arms, legs and fingers. They may also have a curved spine,and their chest sinks in or sticks out. They also have very flexible joints, flat feet, and crowded teeth. Sometimes they could have stretch marks that are not related to weight gain or loss. The internal symptoms are harder to detect but can be very dangerous. Having the syndrome means that the individual has heart problems that are related to aorta, the main artery in the body. Also lungs could suddenly collapse and affected person may have a poor vision. Marfan’s Syndrome is usually not fatal, and people with the disease can usually live normal lives depending on how affected they are.
Genetics: Marfan syndrome is caused by an autosomal dominant allele of the 15th chromosome. There is only one kind of disease, but there are similar disease with similar effects. Marfan syndrome is not sex linked since it affects the 15th chromosome. At least 25% of Marfan syndrome cases of Marfan Syndrome is caused by mutations.
History: A french doctor, Antoine Marfan, discovered the syndrome in 1896, and he decided to name the disease after himself. In the 1990’s scientists at the John Hopkins University and doctors at the Shriners Hospital found the affected gene, and it gave more information to find a cure or at east a way to help the people affected by the syndrome.
Management and treatment: These treatments depend of severity of the condition, this includes a back brace, contact lenses, and glasses. Some surgical procedures include a vitrectomy, endovascualr aneurysm repair, vascular graphing, and heart valve repair. Medications include a beta-blocker and anti hypertensive drugs.
Society and Culture: The severity of the disease depends on the quality of life. Many cases of Marfan does result in a very normal life with some complications and a shortened life expectancy. However, the heart complications, particularly aortic dilation, dissection, rupture, and involvement of the aortic mitral valves, may cause a short life.
Signs of symptoms: Usual features of people with Marfan Syndrome are slightly different for everyone, and they may not all have or experience these symptoms. People affected by Marfan Syndrome are very tall with long arms, legs and fingers. They may also have a curved spine,and their chest sinks in or sticks out. They also have very flexible joints, flat feet, and crowded teeth. Sometimes they could have stretch marks that are not related to weight gain or loss. The internal symptoms are harder to detect but can be very dangerous. Having the syndrome means that the individual has heart problems that are related to aorta, the main artery in the body. Also lungs could suddenly collapse and affected person may have a poor vision. Marfan’s Syndrome is usually not fatal, and people with the disease can usually live normal lives depending on how affected they are.
Genetics: Marfan syndrome is caused by an autosomal dominant allele of the 15th chromosome. There is only one kind of disease, but there are similar disease with similar effects. Marfan syndrome is not sex linked since it affects the 15th chromosome. At least 25% of Marfan syndrome cases of Marfan Syndrome is caused by mutations.
History: A french doctor, Antoine Marfan, discovered the syndrome in 1896, and he decided to name the disease after himself. In the 1990’s scientists at the John Hopkins University and doctors at the Shriners Hospital found the affected gene, and it gave more information to find a cure or at east a way to help the people affected by the syndrome.
Marfan Syndrome
Work Cited:
https://www.nejm.org/doi/full/10.1056/NEJM197204132861502
https://www.medicinenet.com/marfan_syndrome/article.htm#marfan_syndrome_definition_and_facts
https://www.gstatic.com/healthricherkp/pdf/marfan_syndrome.pdf
https://www.marfan.org/about/marfan
https://www.mayoclinic.org/diseases-conditions/marfan-syndrome/symptoms-causes/syc-2035078
https://ghr.nlm.nih.gov/condition/marfan-syndrome
https://www.genome.gov/19519224/learning-about-marfan-syndrome/
http://articles.baltimoresun.com/1991-07-25/news/1991206076_1_marfan-syndrome-connective-tissue-diagnosis
https://kidshealth.org/en/kids/marfan.html